http://www.gavialliance.org http://www.gavialliance.org http://www.gavialliance.org The 2013 Pneumococcal AMC Annual Report gives an overview of the activities linked to the implementation of the pilot Advance Market Commitment from 1 April 2012 to 31 March 2013. During this period a third tender was issued in response to the high level of country demand and eight countries introduced pneumococcal vaccines procured through the AMC, taking the total to 24 introductions by March 2013. http://www.gavialliance.org/library/documents/amc/2013-pneumococcal-amc-annual-report/ http://www.gavialliance.org/library/documents/amc/2013-pneumococcal-amc-annual-report/ Mon, 29 Apr 2013 00:00:00 GMT Learn about Advance Market Commitment, including the pilot AMC for pneumococcal vaccines. http://www.gavialliance.org/library/gavi-documents/amc/fact-sheets/factsheet--advance-market-commitment/ http://www.gavialliance.org/library/gavi-documents/amc/fact-sheets/factsheet--advance-market-commitment/ Fri, 23 Nov 2012 00:00:00 GMT Pneumococcal AMC: OECD GDP Deflator Data Purpose: As per the Pneumococcal AMC Inflation Review Application Process, listed below is the OECD GDP Deflator to be used to calculate an inflation adjustment request. BASE QTR Q2-2009 Q2-2010 Q2-2011 Q2-2012 Q2-2013 Q2-2014 Q2-2015 Q2-2016 Q2-2017 Q2-2018 Q2-2019 Q2-2020 Q2-2 http://www.gavialliance.org/library/documents/amc/pneumococcal-amc-oecd-gdp-deflator-data/ http://www.gavialliance.org/library/documents/amc/pneumococcal-amc-oecd-gdp-deflator-data/ Fri, 09 Nov 2012 00:00:00 GMT ACCELERATE VACCINE INTRODUCTION – PNEUMOCOCCAL CONJUGATE VACCINE Strategic Demand Forecast (Required Supply) Version 5.0 – updated in March 2012 Published – 13 August 2012 This version 5.0 is issued in accordance with the AVI Forecasting Standard Operating Procedure. http://www.gavialliance.org/library/documents/amc/pneumo-strategic-demand-forecast---version-5_0-–-published-13-august-2012/ http://www.gavialliance.org/library/documents/amc/pneumo-strategic-demand-forecast---version-5_0-–-published-13-august-2012/ Thu, 09 Aug 2012 00:00:00 GMT Remaining AMC offer amount: June 2012 http://www.gavialliance.org/library/documents/amc/remaining-amc-offer-amount--june-2012/ http://www.gavialliance.org/library/documents/amc/remaining-amc-offer-amount--june-2012/ Tue, 19 Jun 2012 00:00:00 GMT The 2012 Pneumococcal AMC Annual Report gives an overview of all activities linked to the implementation of the pilot Advance Market Commitment from 1 April 2011 to 31 March 2012. It provides an extensive description of the first achievements of this innovative initiative: the first introductions of pneumococcal vaccines in GAVI countries. http://www.gavialliance.org/library/documents/amc/2012-pneumococcal-amc-annual-report/ http://www.gavialliance.org/library/documents/amc/2012-pneumococcal-amc-annual-report/ Fri, 01 Jun 2012 00:00:00 GMT This document describes early lessons learnt on the selection of a target disease, on core design choices, and on processes related to the pilot Advance Market Commitment (AMC) for pneumococcal vaccines. While ongoing monitoring and evaluations scheduled for the coming years will provide further information about the value of the Pneumo AMC, this document highlights some of the key lessons to date and aims to provide a starting point to inform discussions about the potential applications of the AMC concept to other vaccines or health and non-health interventions. http://www.gavialliance.org/library/gavi-documents/amc/monitoring-and-evaluation/pneumococcal-advance-market-commitment--lessons-learnt-on-disease-and-design-choices-and-processes/ http://www.gavialliance.org/library/gavi-documents/amc/monitoring-and-evaluation/pneumococcal-advance-market-commitment--lessons-learnt-on-disease-and-design-choices-and-processes/ Fri, 30 Sep 2011 00:00:00 GMT Frequently asked questions about Advance Market Commitments for vaccines for manufacturers. http://www.gavialliance.org/library/documents/amc/manufacturers-faqs/ http://www.gavialliance.org/library/documents/amc/manufacturers-faqs/ Mon, 22 Aug 2011 00:00:00 GMT The official formal notification of the remaining AMC Offer Amount. http://www.gavialliance.org/library/documents/amc/remaining-amc-offer-amount--june-2011/ http://www.gavialliance.org/library/documents/amc/remaining-amc-offer-amount--june-2011/ Thu, 16 Jun 2011 00:00:00 GMT The 2011 Pneumococcal AMC Annual Report gives an overview of all activities linked to the implementation of the pilot Advance Market Commitment from 1 April 2010 to 31 March 2011. http://www.gavialliance.org/library/documents/amc/2011-pneumococcal-amc-annual-report/ http://www.gavialliance.org/library/documents/amc/2011-pneumococcal-amc-annual-report/ Fri, 01 Apr 2011 00:00:00 GMT This version 3.0 is issued in accordance with the AVI Forecasting Standard Operating Procedure. The forecast captures all AMC‐eligible demand including countries that: introduce with GAVI support, graduate from GAVI support, and are fully self-financed. http://www.gavialliance.org/library/documents/amc/pneumo-sdf-version-3-0-–-published-on-11-march-2011/ http://www.gavialliance.org/library/documents/amc/pneumo-sdf-version-3-0-–-published-on-11-march-2011/ Fri, 11 Mar 2011 00:00:00 GMT List of modifications to the AMC legal agreements. http://www.gavialliance.org/library/documents/amc/amc-legal-agreements--detailed-list-of-modifications/ http://www.gavialliance.org/library/documents/amc/amc-legal-agreements--detailed-list-of-modifications/ Wed, 09 Mar 2011 00:00:00 GMT Offer agreement relating to the Advance Market Commitment for pneumococcal vaccines. http://www.gavialliance.org/library/documents/amc/revised-amc-offer-agreement/ http://www.gavialliance.org/library/documents/amc/revised-amc-offer-agreement/ Mon, 07 Mar 2011 00:00:00 GMT This Procedures Memorandum describes the procedures that would be applicable to any AMC. http://www.gavialliance.org/library/documents/amc/revised-amc-procedures-memorandum/ http://www.gavialliance.org/library/documents/amc/revised-amc-procedures-memorandum/ Mon, 07 Mar 2011 00:00:00 GMT AMC deed of amendment and restatement relating to the Advance Market Commitment for pneumococcal vaccines offer agreement, IAC Charter & bylaws and procedures memorandum orginally dated 12 June 2009. http://www.gavialliance.org/library/documents/amc/amc-deed-of-amendment-and-restatement/ http://www.gavialliance.org/library/documents/amc/amc-deed-of-amendment-and-restatement/ Mon, 07 Mar 2011 00:00:00 GMT The AMC Baseline Study presents an innovative new approach to public health funding as a way of stimulating and accelerating the development and manufacture of vaccines for developing countries. http://www.gavialliance.org/library/documents/amc/amc-baseline-study/ http://www.gavialliance.org/library/documents/amc/amc-baseline-study/ Fri, 29 Oct 2010 00:00:00 GMT The serotype replacement issue arises from extensive use of pneumococcal conjugate vaccine, which is expected to result in some increase of disease occurence due to serotypes not in the vaccine. This raises question whether the increases could reach a point where the benefit of the vaccine is lost, or the increases will be small relative to the decline in vaccine type disease. http://www.gavialliance.org/library/documents/amc/serotype-replacement-note---prepared-by-the-iac/ http://www.gavialliance.org/library/documents/amc/serotype-replacement-note---prepared-by-the-iac/ Wed, 01 Sep 2010 00:00:00 GMT The purpose of the meeting was to review Pfizer’s application for AMC eligibility for Prevenar 13 and determine if the candidate vaccine met the TPP for the AMC. http://www.gavialliance.org/library/documents/amc/amc-iac-eligibility-determination-meeting--23-august-2010/ http://www.gavialliance.org/library/documents/amc/amc-iac-eligibility-determination-meeting--23-august-2010/ Mon, 23 Aug 2010 00:00:00 GMT The process for manufacturers interested in submitting an Inflation Review Application. http://www.gavialliance.org/library/documents/amc/pneumococcal-amc-inflation-review-application-process/ http://www.gavialliance.org/library/documents/amc/pneumococcal-amc-inflation-review-application-process/ Thu, 29 Jul 2010 00:00:00 GMT The official formal notification of the remaining AMC Offer Amount. http://www.gavialliance.org/library/documents/amc/remaining-amc-offer-amount-2010/ http://www.gavialliance.org/library/documents/amc/remaining-amc-offer-amount-2010/ Wed, 16 Jun 2010 00:00:00 GMT PneumoADIP is a small, dedicated team based at Johns Hopkins Bloomberg School of Public Health, supported by a $30 million grant from the GAVI Alliance. http://www.gavialliance.org/library/documents/amc/pneumoadip/ http://www.gavialliance.org/library/documents/amc/pneumoadip/ Fri, 16 Apr 2010 00:00:00 GMT Minutes from AMC Eligibility Determination Meeting held in London, UK on 16 April 2010. http://www.gavialliance.org/library/documents/amc/minutes-from-amc-eligibility-determination-meeting-april-2010/ http://www.gavialliance.org/library/documents/amc/minutes-from-amc-eligibility-determination-meeting-april-2010/ Fri, 16 Apr 2010 00:00:00 GMT This progress report presents an overview of the activities linked to the implementation of the pneumococcal AMC since the signature of the legal agreements on 12 June 2009 up until 31 March 2010. It was developed by the AMC Secretariat at GAVI, in collaboration with the World Bank and UNICEF’s Supply Division, and was approved by the Independent Assessment Committee on 13 April 2010. http://www.gavialliance.org/library/documents/amc/2010-pneumococcal-amc-annual-report/ http://www.gavialliance.org/library/documents/amc/2010-pneumococcal-amc-annual-report/ Wed, 31 Mar 2010 00:00:00 GMT List of IAC members. http://www.gavialliance.org/library/documents/amc/iac-members/ http://www.gavialliance.org/library/documents/amc/iac-members/ Thu, 12 Nov 2009 00:00:00 GMT The selection process for Independent Assessment Committee (IAC) members is administered by the GAVI Alliance Secretariat, in its role as AMC Secretariat. Evaluation of candidates is conducted by a selection panel composed of five international leaders on global health issues. http://www.gavialliance.org/library/documents/amc/iac-selection-process/ http://www.gavialliance.org/library/documents/amc/iac-selection-process/ Tue, 27 Oct 2009 00:00:00 GMT A case study on the multi-sector effort to build a financing mechanism, the AMC, as an incentive to facilitate vaccine development. http://www.gavialliance.org/library/documents/amc/case-studies-for-global-health---the-world%2cs-first-advance-market-commitment/ http://www.gavialliance.org/library/documents/amc/case-studies-for-global-health---the-world%2cs-first-advance-market-commitment/ Thu, 01 Oct 2009 00:00:00 GMT The process of the Pneumococcal AMC involves donors, IBRD, UNICEF, suppliers, the AMC Independent Assessment Committee (IAC), developing countries and participating manufacturers. http://www.gavialliance.org/library/documents/amc/the-pneumococcal-amc----the-process/ http://www.gavialliance.org/library/documents/amc/the-pneumococcal-amc----the-process/ Wed, 02 Sep 2009 00:00:00 GMT This version 0.1 is issued in accordance with the AVI Forecasting Standard Operating Procedure that foresees the possibility for intermediate updates between official versions when changes in demand exceed predefined thresholds. http://www.gavialliance.org/library/documents/amc/pneumo-sdf-version-0-1-–-published-on-7-august-2009/ http://www.gavialliance.org/library/documents/amc/pneumo-sdf-version-0-1-–-published-on-7-august-2009/ Fri, 07 Aug 2009 00:00:00 GMT Frequently asked questions about the Pneumococcal AMC. http://www.gavialliance.org/library/documents/amc/questions-and-answers-about-the-amc-(faqs)--français-/ http://www.gavialliance.org/library/documents/amc/questions-and-answers-about-the-amc-(faqs)--français-/ Fri, 03 Jul 2009 00:00:00 GMT Frequently asked questions about the Pneumococcal AMC. http://www.gavialliance.org/library/documents/amc/questions-and-answers-about-the-amc-(faqs)/ http://www.gavialliance.org/library/documents/amc/questions-and-answers-about-the-amc-(faqs)/ Fri, 03 Jul 2009 00:00:00 GMT Master definitions schedule relating to the AMC for pneumococcal vaccines. http://www.gavialliance.org/library/documents/amc/master-definitions-agreement/ http://www.gavialliance.org/library/documents/amc/master-definitions-agreement/ Fri, 03 Jul 2009 00:00:00 GMT Pneumococcal vaccine strategic demand forecast corresponding to AMC required supply. http://www.gavialliance.org/library/documents/amc/pneumo-sdf-version-0-–-published-on-12-june-2009/ http://www.gavialliance.org/library/documents/amc/pneumo-sdf-version-0-–-published-on-12-june-2009/ Fri, 12 Jun 2009 00:00:00 GMT The World Bank, The GAVI Alliance and the AMC Donor Committee sought stakeholder input on the planning and design of the pilot AMC through expert groups, consultations, meetings and roundtables. The aim was to incorporate into the design of the AMC the recommendations of economists, global health experts, medical practitioners and scientists from developing and industrialized countries as well as manufacturers and civil society organizations. http://www.gavialliance.org/library/documents/amc/consultation-and-advisory-process/ http://www.gavialliance.org/library/documents/amc/consultation-and-advisory-process/ Mon, 20 Apr 2009 00:00:00 GMT The charter and bylaws of the Independent Assessment Committee (IAC). http://www.gavialliance.org/library/documents/amc/revised-independent-assessment-committee-charter-and-bylaws/ http://www.gavialliance.org/library/documents/amc/revised-independent-assessment-committee-charter-and-bylaws/ Wed, 11 Mar 2009 00:00:00 GMT The process of the Pneumococcal AMC involves donors, IBRD, UNICEF, suppliers, the AMC Independent Assessment Committee (IAC), developing countries and participating manufacturers. http://www.gavialliance.org/library/documents/amc/the-pneumococcal-amc----the-process--français-/ http://www.gavialliance.org/library/documents/amc/the-pneumococcal-amc----the-process--français-/ Sun, 01 Mar 2009 00:00:00 GMT Supplementary informational for the target product profile (TPP) including general information, vaccine characteristics relevant to the TPP, contributors and WHO policy documents. http://www.gavialliance.org/library/documents/amc/tpp-supplementary-information/ http://www.gavialliance.org/library/documents/amc/tpp-supplementary-information/ Thu, 18 Dec 2008 00:00:00 GMT The master table of the target product profile (TPP), product specifications, relate to the public health impact and suitability of the product. http://www.gavialliance.org/library/documents/amc/tpp-master-table/ http://www.gavialliance.org/library/documents/amc/tpp-master-table/ Thu, 18 Dec 2008 00:00:00 GMT Minutes from the AMC Independent Assessment Committee (IAC) meeting on 11 December 2008. http://www.gavialliance.org/library/documents/amc/minutes-from-december-2008-meeting/ http://www.gavialliance.org/library/documents/amc/minutes-from-december-2008-meeting/ Thu, 11 Dec 2008 00:00:00 GMT Codebook to assess whether a pneumococcal vaccine meets the Pneumococcal AMC Target Product Profile for regional vaccine serotype coverage. http://www.gavialliance.org/library/documents/amc/tpp-codebook/ http://www.gavialliance.org/library/documents/amc/tpp-codebook/ Sun, 30 Nov 2008 00:00:00 GMT The report was commissioned by the Monitoring & Evaluation Subgroup of the AMC Donor Committee in August 2007. The monitoring and evaluation proposals contained in this report have been designed to enable the effectiveness, efficiency and eventual impact of this pilot AMC to be measured over time and to assist with its effective management. http://www.gavialliance.org/library/documents/amc/monitoring-and-evaluability-study/ http://www.gavialliance.org/library/documents/amc/monitoring-and-evaluability-study/ Thu, 13 Nov 2008 00:00:00 GMT Minutes from the AMC Independent Assessment Committee (IAC) meeting on 3 November 2008. http://www.gavialliance.org/library/documents/amc/minutes-from-november-2008-meeting/ http://www.gavialliance.org/library/documents/amc/minutes-from-november-2008-meeting/ Mon, 03 Nov 2008 00:00:00 GMT In February 2007, a collective US$1.5 billion for a pilot Advance Market Commitment (AMC) against pneumococcal disease was pledged by the Governments of Italy, the UK, Canada, Russia and Norway, and the Bill & Melinda Gates Foundation. The report recommends the terms on which the AMC will be offered to help developing countries buy new, more effective pneumococcal vaccines. http://www.gavialliance.org/library/documents/amc/iwg-joint-donor-statement/ http://www.gavialliance.org/library/documents/amc/iwg-joint-donor-statement/ Thu, 10 Jul 2008 00:00:00 GMT This report presents the group’s operational recommendations to inform donors’ decisions on AMC design and implementation. It is intended as an addendum to the EEG report, rather than a stand-alone document; therefore, readers will find a number of cross-references. http://www.gavialliance.org/library/documents/amc/implementation-working-group-(iwg)-report/ http://www.gavialliance.org/library/documents/amc/implementation-working-group-(iwg)-report/ Thu, 10 Jul 2008 00:00:00 GMT A report prepared by the Economic Expert Group convened by the GAVI Alliance to provide guidance to the pneumococcal AMC donors about key design decisions using new information available from industry consultations, demand forecasts and modeling of returns to industry under various demand and price scenarios. http://www.gavialliance.org/library/documents/amc/economic-expert-group-(eeg)-report/ http://www.gavialliance.org/library/documents/amc/economic-expert-group-(eeg)-report/ Tue, 01 Apr 2008 00:00:00 GMT This report summarises the results of the All-Party Parliamentary Group for Pneumococcal Disease Prevention in the Developing World (APPG) inquiry into pneumococcal disease in the developing world. http://www.gavialliance.org/library/documents/amc/all-party-parlimentary-group-on-pneumococcal-disease-report/ http://www.gavialliance.org/library/documents/amc/all-party-parlimentary-group-on-pneumococcal-disease-report/ Mon, 17 Mar 2008 00:00:00 GMT The Independent Expert Committee was convened to assess which of the six vaccines included in the Tremonti report would be most suitable for the pilot AMC. http://www.gavialliance.org/library/documents/amc/independent-expert-committee-recommendation-for-amc-pilot/ http://www.gavialliance.org/library/documents/amc/independent-expert-committee-recommendation-for-amc-pilot/ Fri, 29 Jun 2007 00:00:00 GMT In May 2007, the AMC Donor Committee constituted an independent Economic Expert Group (EEG) to advise on the initial AMC design. This document is the donors' response to the EEG report. http://www.gavialliance.org/library/documents/amc/eeg-donor-response/ http://www.gavialliance.org/library/documents/amc/eeg-donor-response/ Sun, 11 Mar 2007 00:00:00 GMT The address Pope Benedict XVI gave to the representatives of the Advance Market Commitment in Rome, Italy on 9 February 2007. http://www.gavialliance.org/library/documents/amc/pope-address-at-vaccine-project-launch/ http://www.gavialliance.org/library/documents/amc/pope-address-at-vaccine-project-launch/ Fri, 09 Feb 2007 00:00:00 GMT Statement from the Bill and Melinda Gates foundation announcing support for the pneumococcal AMC. http://www.gavialliance.org/library/documents/amc/bill-and-melinda-gates-foundation---statement-of-support/ http://www.gavialliance.org/library/documents/amc/bill-and-melinda-gates-foundation---statement-of-support/ Fri, 09 Feb 2007 00:00:00 GMT Remarks of Her Majesty Queen Rania Al-Abdullah on the announcement of Advanced Market Commitments of $1.5 billion in Rome, Italy on 9 February 2007. http://www.gavialliance.org/library/documents/amc/remarks-by-her-majesty-queen-rania-of-jordan-on-the-amc-launch-2007/ http://www.gavialliance.org/library/documents/amc/remarks-by-her-majesty-queen-rania-of-jordan-on-the-amc-launch-2007/ Fri, 09 Feb 2007 00:00:00 GMT